Prostate Health Index - PHI11

The Prostate Health Index (PHI) is a blood test that enhances prostate cancer risk assessment by combining three PSA measurements: total PSA, free PSA, and [-2]proPSA.

PHI provides greater specificity than total or free PSA alone, helping differentiate benign prostate conditions from higher-risk cases and reducing unnecessary biopsies.

It is FDA-approved and recommended in guidelines for early prostate cancer detection, particularly useful when total PSA is in the “gray zone.”