Factor V Leiden (R506Q) Mutation - F5DNA

This genetic test detects the R506Q mutation in the Factor V gene, the most common inherited cause of activated protein C resistance. Having one or two copies of this mutation significantly increases the risk of venous thromboembolism, such as deep vein thrombosis (DVT) or pulmonary embolism (PE).

It is used to assess an individual’s thrombophilia risk, especially in those with unexplained clotting events, family history of thrombosis, or pregnancy complications.